Published on:
    Journal of Cardiovascular Disease Research, 2010; 1(4):171-176
    Review Article | doi:10.4103/0975-3583.74259

    Red wine: A drink to your heart

    Authors:

    T.S. Mohamed Saleem, S. Darbar Basha

    Department of Pharmacology, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet - 516 126, Andhra Pradesh, India

    Abstract:

    Mortality and morbidity are still high in cardiovascular disease (CVD). Myocardial ischemia reperfusion injury leading to myocardial infarction is one of the most frequent causes of the death in humans. Atherosclerosis and generation of reactive oxygen species through oxidative stress is the major risk factor for CVD. From the literature collection, it has been identifi ed that moderate consumption of red wine helps in preventing CVD through several mechanisms, including increasing the high-density lipoprotein cholesterol plasma levels, decreasing platelet aggregation, by antioxidant effects, and by restoration of endothelial function. The aim of this review is to discuss the accumulating evidence that suggests that red wine possesses a diverse range of biological actions and may be benefi cial in the prevention of CVD.

    Key words: Alcohol, flavonoids, grape juice, polyphenols, resveratrol, wine research.