Diabetic retinopathy (DR) is one of the most common complications of diabetes and is a lending cause of blindness in people of the working age in Western countries. A major pathology of DR is microvascular complications such as non-perfused vessels,microaneurysms,dot/blot hemorrhages,cotton-woolspots, venousbeading,vascular leakage and neovacularization. Multiple mechanisms are involved in these alternations. This review will focus on the role of inflammation in diabetic retional microvascular complications and discuss the potetial therapies by targeting inflammation.
Key words: Diabetic retinopathy, inflammation, microvascular complications