Published on:
    Journal of Cardiovascular Disease Research, 2012; 3(1):22-25
    ORIGINAL ARTICLE | doi:10.4103/0975-3583.91599

    Effect of endurance and strength exercise on release of brain natriuretic peptide

    Authors:

    Somayeh Bordbar, Mohammad Ali Babaee Bigi1, Amir Aslani1, Eskandar Rahimi, Nader Ahmadi

    Fars Sciences and Research Branch, Azad University, Shiraz,

    1Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Abstract:

    Objectives: The aim of this study was to investigate the effects of 8-week endurance and resistance exercise training on release of brain natriuretic peptide. Materials and Methods: Study population was categorized into 4 groups: Group-1 (n = 6) consisted of sedentary individuals who volunteered to complete 8-weeks of endurance exercise; Group-2 (n=6) consisted of sedentary individuals who volunteered to complete 8-weaks of resistance exercise. Three blood samples [for Terminal pro BNP (NT-Pro-BNP)] were taken before, immediately after exercise and after 8 weeks of exercise training. Results: NT-Pro BNP was significantly increased immediately after endurance exercise [from 37.9 ± 1.4 pg/ml to 52.1 ±1.5 pg/ml; P = 0.002] and was decreased to 23.2 ± 9.3 pg/ml after 8 weeks of endurance exercise [P = 0.013]. On the other hand, NT-Pro BNP showed no significant changes immediately after resistance exercise [from 26.6 ± 4.9 pg/ml to 24.1 ±4.5 pg/ml; P = 0.553]. In contrast, NT-Pro BNP was significantly increased to 39.5 ±1.6 pg/ml after 8 weeks of resistance exercise [P = 0.012]. Conclusion: Endurance exercise training reduces circulating NT-Pro BNP concentration, which is likely a marker of reduced ventricular wall tension and improved myocardial function. In contrast, strength exercise induces significant increase in NT-Pro BNP, which could be partially attributed to myocardial damage.

    Key words:Brain natriuretic peptide, endurance exercise, strength exercise.