Published on:
    Journal of Cardiovascular Disease Research, 2013; 4(4):254-256
    Clinical Case Reports Based Study | doi:10.1016/j.jcdr.2013.06.003

    Spontaneous endocarditis caused by rapidly growing non-tuberculous Mycobacterium chelonae in an immunocompetent patient with rheumatic heart disease

    Authors:

    Naveena Jagadeesan a, Soumya Patra b,*, Ajit Pal Singh b, Chamrajnagar Mahadevappa Nagesh b, Babu Reddy b, Srinivas C. Badnur b, Manjunath Cholenahally Nanjappa b

    a Department of Microbiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India

    b Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore 560069, Karnataka, India

    Abstract:

    We are reporting the first case of spontaneous endocarditis caused by rapid grower non-tuberculous Mycobacterium chelonae in a case of rheumatic heart disease. The diagnosis was confirmed as there was repeated isolation of rapidly growing atypical Mycobacterium from blood culture which was identified as M. chelonae by Reverse line probe assay. The patient presented with pyrexia of unknown origin. Later she was found to have rheumatic heart disease with severe aortic regurgitation & large vegetation was seen attached to the aortic valve. She was treated with rifampicin, clarithromycin, amikacin & levofloxacin based on culture & sensitivity. She succumbed to her illness after development of large cerebral infarction due to embolization of vegetation from aortic valve.

    Key words: Non-tuberculous mycobacteria, Aortic valve, Endocarditis, Mycobacterium chelonae, Rheumatic heart disease.