Published on:
    Journal of Cardiovascular Disease Research, 2012; 3(2):160-164
    CLINICAL CASE REPORT BASED STUDY | doi:10.4103/0975-3583.95375

    Pheochromocytoma with inferior vena cava thrombosis: An unusual association


    Sunil K. Kota, Siva K. Kota1, Sruti Jammula2, Lalit K. Meher3, Kirtikumar D. Modi

    Departments of Endocrinology, Medwin Hospital, Hyderabad, Andhra Pradesh,

    1Anaesthesia, Central Security Hospital, Riyadh, Saudi Arabia.

    2Pharmaceutics, Roland Institute of Pharmaceutical Sciences,

    3Medicine, MKCG Medical College, Berhampur, Orissa, India,


    Pheochromocytomas have been described in association with vascular abnormalities like renal artery stenosis. A 48-year-old man was admitted to our hospital with the complaints of headache, sweating, anxiety, dizziness, nausea, vomiting and hypertension. For last several days, he was having a dull aching abdominal pain. Abdominal computed tomography (CT) revealed the presence of a left adrenal pheochromocytoma. An inferior vena cava (IVC) venogram via the right jugular vein demonstrated occlusion of the IVC inferior to the right atrium. Surgical removal of pheochromocytoma was done, followed by anticoagulant treatment for IVC thrombosis, initially with subcutaneous low molecular weight heparin, and then with oral warfarin, resulting in restoration of patency. To the best of our knowledge, the occurrence of pheochromocytoma in IVC thrombosis has not been reported so far from India. Possible mechanisms of such an involvement are discussed.

    Key words:Anticoagulant, hypertension, inferior vena cava thrombosis, pheochromocytoma.