Published on:
    Journal of Cardiovascular Disease Research, 2012; 3(4):287-289
    ORIGINAL ARTICLE | doi:10.4103/0975-3583.102702

    Comparison of microalbuminuria w ith hs-CRP and low density lipoprotein levels in nondiabetic, nonhypertensive myocardial infarction patients

    Authors:

    B. K. Manjunatha Goud, Bhavna Nayal1, Oinam S. Devi2, R. N. Devaki3, S. S. Avinash4, T. G. Satisha5, C. V. Raghuveer6

    Department of Biochemistry, RAK Medical and Health Sciences University, Ras Al Khaimah, U.A.E,

    1Department of Pathology, KMC, Manipal University, Manipal,

    2Department of Nursing, Vidya Nursing College, Kapu, Udupi,

    3Department of Biochemistry, JSS Medical College, JSS University, Mysore,

    4Department of Biochemistry, Father Muller Medical College, Mangalore,

    5Department of Biochemistry, Siddartha Medical College, Tumkur,

    6Department of Pathology and Medical Director, SIMS, Mukka, Mangalore, India.

    Abstract:

    Introduction: Microalbuminuria (MA), defined as urine albumin to urine creatinine ratio (UACR) of 30 to 300 mg/G of creatinine, is an established risk factor for cardiovascular morbidity and mortality and for end-stage renal disease in individuals with an adverse cardiovascular risk profile such as those with hypertension or/and diabetes mellitus. Materials and Methods: Thirty five patients were included in the study and equal number of age- and sex-matched controls were also included. 2 ml of venous blood was collected for hs-CRP determination and early morning mid stream urine sample was collected under strict aseptic precautions. The lipid profile was estimated in cobas autoanalyzer. Results:There was significant increase in levels of Low density lipoprotein (LDL) cholesterol, microalbumin, and hs-CRP (P< 0.001) in patients with myocardial infarction compared to healthy controls. Conclusion: Therefore, MA and hsCRP evaluation may have potential role in improving cardiovascular risk prediction, when used along with traditional lipid profiles.

    Key words: Low density lipoprotein cholesterol, microalbumin, myocardial infarction, Non diabetics.