Anaphylactic shock in periprocedural period poses diagnostic and therapeutic challenge. Here we report a case of severe mitral stenosis developed sudden cardio respiratory arrest after parenteral antibiotic injection while being prepared for elective balloon mitral valvotomy. After initial resuscitation patient was taken up for emergency balloon mitral valvotomy in view of referactory shock. Patient developed air embolism during the procedure in view of reduced right atrial pressure which was successfully managed. She underwent balloon mitral valvotomy. Patient developed renal failure and deranged haematological parameters which were managed accordingly, finally the patient made a complete recovery.
Key words: Anaphylactic shock, Air embolism, Balloon mitral valvotomy.