Published on:March 2017
    Journal of Cardiovascular Disease Research, 2017; 8(1):28-30
    Case Report | doi:10.5530/jcdr.2017.1.6

    Negative Pressure Pulmonary Oedema after Sedation in a Patient Undergoing Pacemaker Implantation


    Venkatesh Tekur Krishnamurthy, Sri Arun Tekur Venkatesh*

    Department of Cardiology, Apollo hospitals 154/11, Opp IIM-B, Bannerghatta Road Bangalore 560076 India.


    Negative pressure pulmonary oedema (NPPE) is a manifestation of upper airway obstruction and is seen after extubation postoperatively. The large negative intrathoracic pressure generated by forced inspiration against an obstructed airway is thought to be the principal mechanism involved. It is a dangerous and potentially fatal condition with a multifactorial pathogenesis. The Authors report a case of negative pressure pulmonary oedema occurring periprocedurally while undergoing permanent pacemaker implantation under local anaesthesia and light sedation due to upper airway obstruction caused by falling back of the tongue.

    Key words: Negative pressure pulmonary oedema, Sedation, permanent pacemaker implantation, Upper airway obstruction.

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